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KaCrole Higgins was diagnosed with breast cancer in 2020. “In May 2020, I found a lump in my breast. I cried. By June, it was diagnosed as breast cancer, triple positive, stage 1A. While getting this cancer diagnosis was devastating, it also became an opportunity. Suddenly, the cancer gave me clarity. It gave me clarity about what was important, what was good in my life, what was toxic in my life, and what I needed to do.” Click below to read more of KaCrole’s story

https://momentum.vicc.org/2022/04/cancer-gave-me-clarity/

If Landon Ryan had been diagnosed with bilateral retinoblastoma 10, 20 or 30 years ago, she might not be here today with nearly perfect vision.Thanks to recent improvements in the treatment for this rare form of cancer that almost exclusively affects children under the age of 5, the diagnosis had the power to change Landon’s life when she was 11 months old, but not to take it — or her eyesight. Click below to learn more about Landon and her story.

https://momentum.vicc.org/2022/04/brighter-outlook/
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A Phase II Study of Cabozantinib for Patients with Recurrent or Progressive Meningioma

Neuro-Oncology

Neuro-Oncology
II
Mohler, Alexander
NCT05425004
VICC-ITNEU23261

A Randomized Phase 2 Trial of ASTX727 +/- Iadademstat in Accelerated/Blast-Phase Philadelphia Chromosome-Negative Myeloproliferative Neoplasms (MPNs)

Leukemia

Leukemia
II
Kishtagari, Ashwin
NCT06661915
ETCHEM10675

Optimizing Antibody-Drug Conjugate Therapy Through Molecular Analysis for Therapy Choice (ADC MATCH)

Multiple Cancer Types

Adrenocortical, Bladder, Breast, Cervical, Colon, Dermatologic, Esophageal, GIST, Gastric/Gastroesophageal, Gastrointestinal, Gynecologic, Head/Neck, Kidney (Renal Cell), Liver, Lung, Melanoma, Miscellaneous, Ovarian, Pancreatic, Prostate, Rectal, Sarcoma, Thyroid, Urologic, Uterine
II
Keedy, Vicki
NCT06311214
ETCMD10397

Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

Not Available
II
Not Available
NCT05919108
VICC-NCBRE23172

A Phase II Trial of Durvalumab with Gemcitabine and Cisplatin as Neoadjuvant Therapy for High-Risk Resectable Intrahepatic Cholangiocarcinoma

Not Available
II
Heumann, Thatcher
NCT06050252
ETCGI10608

Phase II Trial of Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

Neuroblastoma (Pediatrics)

Neuroblastoma (Pediatrics)
II
Benedetti, Daniel
NCT06540963
VICCPED24540

A Phase II, Single Arm, Open Label, Long Term Safety Rollover Trial of Oral Brigimadlin in Patients with Solid Tumors.

Miscellaneous

Miscellaneous
II
Keedy, Vicki
NCT06619509
VICCSAR24625

Phase 2 Study of Tovorafenib (DAY101) in Relapsed and Refractory Langerhans Cell Histiocytosis

Not Available
II
Not Available
NCT05828069
VICC-NTPED24012