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Colorectal cancer 'cartography' reveals an avenue to improved immunotherapy

Vanderbilt University Medical Center researchers have discovered why most colorectal tumors escape detection and destruction by the body's immune system.

https://news.vumc.org/2023/12/11/colorectal-cancer-cartography-reveals-an-avenue-to-improved-immunotherapy/

Mon, 12/11/2023 - 12:00

Gastrointestinal_Cancer_Research_Program

Bill Snyder

Locked

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

Multiple Cancer Types

The primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combination with other anticancer drug(s), and to determine the optimal dose of E7386 in combination with lenvatinib in endometrial carcinoma (EC) (for EC Dose Optimization Part only).

Disease Sites: Gynecologic, Liver, Phase I

Phase: I

Investigator: Brown, Alaina

NCTID: NCT04008797

Protocol No: VICC-DTPHI23106

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