De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
                                                                                                                                                                                                                                                                                                
              
  
          
              Breast
              
      
          
  
  Breast
              This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.
          
          
                      Breast
                  
      
              
        
          
                    
  
              III
          
        
        
      
              
        
          
                    
  
              Chak, Bapsi
          
        
        
      
              
        
          
                    
  
              NCT04852887
          
        
        
      
              
        
          
                    
  
              NRGBREBR007