Clinical Trials Search at Vanderbilt-Ingram Cancer Center

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Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid / Round Cell Liposarcoma

Sarcoma

This is a study to investigate the efficacy and safety of ADP-A2M4 in HLA-A*02 eligible and MAGE-A4 positive subjects with metastatic or inoperable (advanced) Synovial Sarcoma (Cohort 1 and Cohort 2) or MRCLS (Cohort 1) .

Disease Sites: Sarcoma

Phase: II

Investigator: Keedy, Vicki

NCTID: NCT04044768

Protocol No: VICCSAR1948

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SPEARHEAD 2 Study in Subjects With Recurrent or Metastatic Head and Neck Cancer

Head/Neck

This is a study to investigate the efficacy and safety of ADP-A2M4 in combination with pembrolizumab in HLA-A*02 eligible and MAGE-A4 positive subjects with recurrent or metastatic Head and Neck cancer.

Disease Sites: Head/Neck

Phase: II

Investigator: Gibson, Mike

NCTID: NCT04408898

Protocol No: VICCHN2034

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