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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



A Phase 1, Dose-Escalation Study to Evaluate Safety and Tolerability of Belzutifan (MK-6482) in Participants with Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

Multiple Cancer Types

Kidney (Renal Cell), Phase I
I
Beckermann, Kathryn
NCT04846920
VICCUROP2127

A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)

Bladder

The primary objective of this study is to compare belzutifan to everolimus with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as assessed by Blinded Independent Central Review (BICR) and to compare everolimus with respect to overall survival (OS). The hypothesis is that belzutifan is superior to everolimus with respect to PFS and OS.
Bladder
III
Beckermann, Kathryn
NCT04195750
VICCURO19114

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