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A Study to See if Memantine Protects the Brain during Radiation Therapy Treatment for a Brain Tumor

Multiple Cancer Types

This phase III trial compares memantine to usual treatment in treating patients with brain tumors that are newly diagnosed or has come back (recurrent). Memantine may block receptors (parts of nerve cells) in the brain known to contribute to a decline in cognitive function. Giving memantine may make a difference in cognitive function (attention, memory, or other thought processes) in children and adolescents receiving brain radiation therapy to treat a primary brain tumor.
Neuro-Oncology, Pediatrics
III
Esbenshade, Adam
NCT04939597
COGACCL2031

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