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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



Prospective, Randomized, Crossover Trial Comparing Recombinant von Willebrand Factor (rVWF) vs. Tranexamic Acid (TA) to Minimize Menorrhagia in Women with von Willebrand Disease: The VWD Minimize Study

Multiple Cancer Types

Gynecologic, Hematologic
III
Wheeler, Allison
NCT02606045
VICCNCBH1961

Characterization of Central Pain Syndrome in Survivors of Head and Neck Cancer

Head/Neck

This trial studies the characterization of central pain syndrome in survivors of head and neck cancer. Many head and neck cancer patients have pain after they have completed treatment. Cancer and its treatment may change how the brain manages pain. This can make treatment of post-treatment pain more challenging for health care provides. This trial is being done to better understand how the brain is responding to pain.
Head/Neck
N/A
Lou, Dianne
NCT04128267
VICCHN1982

Long Term Follow-up for Early Detection of Lung Cancer in Current or Former Smokers

Lung

This research trial studies the long term follow-up for early detection of lung cancer in current or former smokers. Following up on smokers by collecting and analyzing specimens in the laboratory, performing chest computed tomography (CT) scans, as well as reviewing medical records may help doctors detect lung cancer at an earlier stage.
Lung
N/A
Grogan, Eric
NCT03181256
VICCTHO1730

Prospective Observational Trial of an Absorbable Hydrogel Spacer in Prostate Cancer Radiotherapy

Prostate

Prostate
N/A
Kirschner, Austin
VICCURO16112

DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma

Lung

Patients with malignant pleural mesothelioma (MPM) that cannot be surgically removed will receive first-line treatment with standard chemotherapy of pemetrexed and cisplatin. Two-thirds of the participants in the study will be randomly assigned to also receive a new treatment called durvalumab. Durvalumab is an antibody (a type of human protein) that works by blocking a body substance called Programmed Death-Ligand 1 (PD-L1). Blocking PD-L1 helps the body's immune system attack cancer cells. Research has shown that durvalumab can slow tumor growth and shrink tumors in some people with cancer. Previous studies of combining durvalumab and chemotherapy showed that this combination is active in advanced mesothelioma. The purpose of this study is to see whether adding durvalumab to standard chemotherapy will improve overall survival (OS) in patients with MPM.
Lung
III
Gillaspie, Erin
NCT04334759
VICCTHO20128

An Open Label Study Evaluating the Efficacy and Safety of AB928 Based Treatment Combinations in Patients With Metastatic Colorectal Cancer.

Multiple Cancer Types

This randomized phase 1b / 2 open-label study will evaluate the efficacy of etrumadenant (AB928) treatment combinations in patients with metastatic colorectal cancer.
Colon, Rectal
I/II
Eng, Cathy
NCT04660812
VICCGIP2113

Long-Term Follow-Up Study for Subjects Treated With P-BCMA-101

Hematologic

Subjects are enrolled in this study following completion or early discontinuation from a Poseida sponsored or supported study of P-BCMA-101 T cells and will be followed for a total of 15 years post treatment from the last P-BCMA-101 treatment. Subjects will be monitored for safety and efficacy to assess the risk of delayed adverse events (AEs) and assess long-term efficacy, and PK and quantification of P-BCMA-101 T cells. Rimiducid may be administered as indicated.
Hematologic
I
Dholaria, Bhagirathbhai
NCT03741127
VICCCTT20114

Pembrolizumab Plus Lenvatinib for First-line Advanced / Metastatic Non-clear Cell Renal Cell Carcinoma (1L nccRCC) (MK-3475-B61)

Kidney (Renal Cell)

This study is being performed as a single-arm open-label study in order to rapidly provide information on the potential benefits of the combination of pembrolizumab and lenvatinib in participants with previously untreated advanced / metastatic non-clear cell renal cell carcinoma.
Kidney (Renal Cell)
II
Beckermann, Kathryn
NCT04704219
VICCURO20115


Comparing Two Methods to Follow Patients with Pancreatic Cysts

Pancreatic

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts. The study doctors want to compare more frequent monitoring vs less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.
Pancreatic
N/A
Tan, Marcus
NCT04239573
ECOGGIEA2185

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