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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



Genetic Testing in Screening Patients with Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

Multiple Cancer Types

This trial screens patients with colon or rectal cancer that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable) for genetic mutations for recommendation to a molecularly assigned therapy. Identifying gene mutations may help patients enroll onto target companion trials that target these mutations.
Colon, Rectal
N/A
Ciombor, Kristen
NCT03765736
VICCGI2011

Long Term Follow-up for Early Detection of Lung Cancer in Current or Former Smokers

Lung

This research trial studies the long term follow-up for early detection of lung cancer in current or former smokers. Following up on smokers by collecting and analyzing specimens in the laboratory, performing chest computed tomography (CT) scans, as well as reviewing medical records may help doctors detect lung cancer at an earlier stage.
Lung
N/A
Massion, Pierre
NCT03181256
VICCTHO1730

Early Onset Pulmonary Events in Patients with Non-Small Lung Cancer or Other Cancers Taking Brigatinib or Other TKIs

Multiple Cancer Types

This phase II trial studies early onset pulmonary events in patients with non-small lung cancer and other cancers taking brigatinib or other TKIs. Severe side effects, including trouble breathing, coughing, pneumonia, and inflammation of the lungs (pneumonitis), have been seen in patients taking brigatinib. This study is being done to watch patients taking brigatinib and compare that experience with patients taking other drugs that also target ALK or ROS1 to study how often events like these occur. This study is also being done to observe patients who stopped brigatinib temporarily because of a suspected early onset pulmonary event, but then restarted brigatinib at the same dose to assess what experience they have.
Lung, Non Small Cell
II
Iams, Wade
NCT03389399
VICCTHO1885

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients with Prostate Cancer

Prostate

This phase II trial studies how well multiparametric magnetic resonance imaging (MRI) works in evaluating cancer stage and helping treatment planning in patients with prostate cancer. Multiparametric MRI may be useful for evaluating the type of cancer in finding aggressive disease.
Prostate
II
Planz, Virginia
NCT03697148
ECOGUROEA8171

Navigation Endoscopy for the Diagnosis of Indeterminate Lung Nodules, VERITAS Study

Lung

This trial studies how well navigation endoscopy works in diagnosing indeterminate lung nodules. Navigation bronchoscopy is a procedure using technology designed to guide a flexible bronchoscope (a small tube with a camera) through the natural airway route (wind-pipe and bronchi) to access the nodule. Navigation bronchoscopy may be more accurate than the standard computed tomography (CT)-guided biopsy in diagnosing patients with indeterminate lung nodules.
Lung
N/A
Maldonado, Fabien
NCT04250194
VICCTHO19102

Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy

Lung

This trial studies how well rapid on site evaluation of pleural touch preparations works in diagnosing cancerous fluid in between the linings of the lungs (malignant pleural effusion) in patients undergoing a pleuroscopy. A type of laboratory testing called rapid on site evaluation of pleural touch preparations that uses pleural biopsy tissue samples collected during an already-scheduled pleuroscopy may be able to diagnose malignant pleural effusion.
Lung
N/A
Maldonado, Fabien
NCT03868579
VICCTHO1991

Characterization of Central Pain Syndrome in Survivors of Head and Neck Cancer

Head/Neck

This trial studies the characterization of central pain syndrome in survivors of head and neck cancer. Many head and neck cancer patients have pain after they have completed treatment. Cancer and its treatment may change how the brain manages pain. This can make treatment of post-treatment pain more challenging for health care provides. This trial is being done to better understand how the brain is responding to pain.
Head/Neck
N/A
Lou, Dianne
NCT04128267
VICCHN1982

Comparing Two Methods to Follow Patients with Pancreatic Cysts

Pancreatic

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts. The study doctors want to compare more frequent monitoring vs less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.
Pancreatic
N/A
Tan, Marcus
NCT04239573
ECOGGIEA2185

Contrast-Enhanced Ultrasound Imaging in Diagnosing Liver Cancer in Patients with Cirrhosis

Liver

This clinical trial studies how well contrast-enhanced ultrasound imaging works in diagnosing liver cancer in patients with cirrhosis. Diagnostic procedures, such as contrast-enhanced ultrasound imaging, may help find and diagnose liver cancer.
Liver
N/A
Planz, Virginia
NCT03318380
VICCGI19104

A Phase 2 Study of Cabozantinib in combination with Atezolizumab as Neoadjuvant Treatment for muscle-invasive Bladder Cancer (ABATE)

Bladder

Bladder
II
Davis, Nancy
NCT04289779
VICCURO2044

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