Skip to main content

Clinical Trials Search at Vanderbilt-Ingram Cancer Center



Olaparib and Entinostat in Treating Patients with Recurrent, Platinum-Refractory or Resistant Ovarian, Primary Peritoneal, or Fallopian Tube Cancers

Multiple Cancer Types

This phase I / II trial studies the side effects and best dose of olaparib and entinostat and to see how well they work in treating patients with ovarian, primary peritoneal, or fallopian tube cancers that have come back or do not respond to platinum-based chemotherapy. Tumor samples from patients will be tested for a specific change in their genetic materials (DNA) called homologous recombination deficiency (HRD). Patients who lack this genetic change will be eligible to participate in this study. Olaparib and entinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Gynecologic, Ovarian
I/II
Crispens, Marta
NCT03924245
VICCGYN1842

To learn more about any of our clinical
trials, call 1-800-811-8480 or complete
the online Self-Referral Form here: