The immune system underlies the pathophysiology of nearly every disease, yet therapies that modulate immunity for clinical benefit have yet to reach their full potential. My laboratory works at the interface of engineering and immunology to improve human health through the design of novel molecularly engineered materials that tightly regulate the delivery of immunomodulatory signals to the organs, cells, and intracellular pathways of the immune system. We are particularly interested in leverage our interdisciplinary expertise in polymer chemistry, nanomedicine, drug delivery and immunobiology to innovate new approaches to modulate the tumor microenvironment and enhance cellular immune responses to cancer vaccines.