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KaCrole Higgins was diagnosed with breast cancer in 2020. “In May 2020, I found a lump in my breast. I cried. By June, it was diagnosed as breast cancer, triple positive, stage 1A. While getting this cancer diagnosis was devastating, it also became an opportunity. Suddenly, the cancer gave me clarity. It gave me clarity about what was important, what was good in my life, what was toxic in my life, and what I needed to do.” Click below to read more of KaCrole’s story

https://momentum.vicc.org/2022/04/cancer-gave-me-clarity/

If Landon Ryan had been diagnosed with bilateral retinoblastoma 10, 20 or 30 years ago, she might not be here today with nearly perfect vision.Thanks to recent improvements in the treatment for this rare form of cancer that almost exclusively affects children under the age of 5, the diagnosis had the power to change Landon’s life when she was 11 months old, but not to take it — or her eyesight. Click below to learn more about Landon and her story.

https://momentum.vicc.org/2022/04/brighter-outlook/

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Expanded Access Program (EAP) for Obecabtagene Autoleucel (Obe-Cel) Out-of-Specification (OOS) in Adult Patients with Acute Lymphoblastic Leukemia

Leukemia

Disease Sites: Leukemia

Phase: N/A

Investigator: Oluwole, Olalekan

NCTID:

Protocol No: VICC-CTT25006

High-Resolution Specimen PET-CT Imaging for the Intraoperative Visualization of Resection Margins: An Exploratory Study

Miscellaneous

Disease Sites: Miscellaneous

Phase: I

Investigator: Topf, Michael

NCTID:

Protocol No: VICCHNP24616

A Randomized Phase II Study of AMG 510 (Sotorasib) With or Without Panitumumab in Advanced Solid Tumors: A ComboMATCH Treatment Trial

Disease Sites: Not Available

Phase: II

Investigator: Choe, Jennifer

NCTID: NCT05638295

Protocol No: ECOGMDEAY191-E5

A Phase 2, Open-Label, Randomized, Multicenter Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease

Disease Sites: Not Available

Phase: II

Investigator: Kitko, Carrie

NCTID: NCT06388564

Protocol No: VICC-DTCTT24000

Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT)

Multiple Cancer Types

Disease Sites: Pediatrics, Wilms / Other Kidney (Pediatrics)

Phase: II

Investigator: Benedetti, Daniel

NCTID: NCT04322318

Protocol No: COGAREN1921

A Phase 1/2 Study of LY3537982 in Patients with KRAS G12C-Mutant Advanced Solid Tumors

Disease Sites: Not Available

Phase: I/II

Investigator: Not Available

NCTID: NCT04956640

Protocol No: VICCTHOP2155

An International Pilot Study of Chemotherapy and Tyrosine Kinase Inhibitors with Blinatumomab in Patients with Newly-Diagnosed Philadelphia Chromosome-Positive or ABL-class Philadelphia Chromosome-Like B-cell Acute Lymphoblastic Leukemia

Leukemia

Disease Sites: Leukemia

Phase: III

Investigator: Smith, Brianna

NCTID: NCT06124157

Protocol No: COGAALL2131

A Phase 3 Randomized Trial for Patients with de novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO, and the Addition of the FLT3 Inhibitor Gilteritinib for Patients with FLT3 Mutations

Disease Sites: Not Available

Phase: III

Investigator: Not Available

NCTID: NCT04293562

Protocol No: COGAAML1831

Phase 3 Multicenter, Randomized, Open-label, Active-Controlled Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb for Treatment-nave Subjects With Metastatic Colorectal Cancer With KRAS p.G12C Mutation (CodeBreaK 301)

Disease Sites: Not Available

Phase: III

Investigator: Eng, Cathy

NCTID: NCT06252649

Protocol No: VICC-DTGIT23266

Phase 2 Study of Ruxolitinib-Based Primary Treatment for Acute GVHD

Multiple Cancer Types

Disease Sites: Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndrome

Phase: II

Investigator: Kitko, Carrie

NCTID: NCT06936566

Protocol No: VICCCTT25042