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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer

Breast

This clinical trial will assess the safety and early efficacy of Hydroxychloroquine or Avelumab, with or without Palbociclib, in early-stage ER+ breast cancer patients who are found to harbor disseminated tumor cells (DTCs) in the bone marrow after definitive surgery and standard adjuvant therapy.
Breast
II
Reid, Sonya
NCT04841148
VICCBRE2161


NMTT-Neuroblastoma Maintenance Therapy Trial Using Difluoromethylornithine (DFMO)

Multiple Cancer Types

Endocrine, Neuroblastoma (Pediatrics), Neuroendocrine, Pediatrics
II
Pastakia, Devang
NCT02679144
VICCPED16157

Expanded Access Program (EAP) for Obecabtagene Autoleucel (Obe-Cel) Out-of-Specification (OOS) in Adult Patients with Acute Lymphoblastic Leukemia

Leukemia

Leukemia
N/A
Oluwole, Olalekan
VICC-CTT25006

An Open-label, Phase 1 Dose Escalation and Phase 2 Dose Expansion Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of SMP-3124LP in Adults with Advanced Solid Tumors

Multiple Cancer Types

Breast, Head/Neck, Lung, Non Small Cell, Ovarian, Phase I, Uterine
I/II
Eng, Cathy
NCT06526819
VICC-DTPHI23348



Randomized Phase II Trial of Anti-LAG-3 and Anti-PD-1 Blockade vs SOC in Patients with Recurrent Glioblastoma

Neuro-Oncology

Neuro-Oncology
II
Mohler, Alexander
NCT06325683
ALLNEUA072201

A First-In-Human, Phase 1, Dose-Escalation Study of SGR-3515 In Participants with Advanced Solid Tumors

Not Available
I
Gibson, Mike
NCT06463340
VICC-DTPHI24100

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

The main purpose of this study is to assess the efficacy and safety of volrustomig compared to observation in participants with unresected locally advanced head and neck squamous cell carcinoma (LA-HNSCC) who have not progressed after receiving definitive concurrent chemoradiotherapy (cCRT).
Not Available
III
Choe, Jennifer
NCT06129864
VICC-DTHAN24071

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