Andreana Holowatyj, Ph.D., M.Sc
- Assistant Professor of Medicine
- Assistant Professor of Cancer Biology
Phone
Suite 334-G
Nashville, TN 37232
Andreana Holowatyj, Ph.D., M.Sc
- Assistant Professor of Medicine
- Assistant Professor of Cancer Biology
615-322-0105
andreana.holowatyj@vumc.org
Suite 334-G
Nashville, TN 37232
Research Program
Departments/Affiliations
Profile
I am an Assistant Professor of Medicine and Cancer Biology at the Vanderbilt University Medical Center andVanderbilt-Ingram Cancer Center (VICC) with research projects spanning from gastrointestinal cancer etiologyto survivorship, including both patient studies and laboratory projects. I have authored or coauthored 49publications, centered upon cancer epidemiology and biology—with a particular focus on cancers amonadults younger than age 50 years. My research has been supported by: Susan G. Komen for the Cure(Graduate Training in Disparities Research Fellowship), NHGRI (T32 HG008962), NICHD (K12 HD043482),the Dalton Family Foundation and American Cancer Society. I also serve on the Board of Directors for theYoung Adult Cancers Program at VICC, on the American Joint Committee on Cancer (AJCC) LowerGastrointestinal Tract Expert Panel, and recently served as a Co-Investigator on an R01 that fine-mapping andfunctional analysis of CRC risk loci (R01 CA188214). Broadly, my research expertise centers upon my dualtraining as a basic scientist and clinical/molecular epidemiologist and underscores my strong preparednessand ability to lead clinical reproductive science research in early-onset colorectal cancer (CRC) patients. I havedeveloped, led and been a key contributor to leading studies in early-onset CRC clinical outcomes andepidemiology, in CRC survivorship, in the distinct molecular features ofearly-onset CRC and in the clinical and biological spectrum of other early-onset cancers.Together, these findings underscore my long-term goal to disentangle and definethe unique clinical and biological burden of early-onset cancers—particularly early-onset CRC—in order todrive the development and delivery of tailored strategies that will improve clinical outcomes specifically to thispopulation. Aligned with this unique expertise, the overarching goal of this project is to identify changes ingonadal function caused by CRC treatments and investigate psychosocial dimensions of sexual health andfertility—after a diagnosis of early-onset CRC. This project uniquely utilizes my prospective cohort study ofearly-onset CRC patients at VICC, the PREFACE Study, and is projected to be approximately 11-fold largerthan previous fertility-related studies in this population. As such, results from this clinical study are powered togenerate new data that will lead to incorporating reproductive health care into the clinical management of early onsetCRC.
Education
- M.Sc., University of Utah School of Medicine, Salt Lake City, UT (2018)
- Ph.D., Wayne State University, Detroit, MI, (2017)
- B.A., Benedictine University, Lisle, IL, (2013)
Post-Doctoral Training
- Post-Doctoral Fellow, Huntsman Cancer Institute, Salt Lake City, UT (2017-2019)