A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.

David Cortez, PhD, Richard N. Armstrong Professor of Innovation in Biochemistry and professor of biochemistry, has been named interim chair in the Department of Biochemistry beginning Jan. 1, 2021.

For the second time, cancer researchers at Vanderbilt have discovered a protein that—when genetically manipulated to impede it from interacting with a gene responsible for cancer genesis—effectively melts tumors in days.

Transcription factors — proteins that regulate gene expression — play critical roles in cell fate decisions and are frequent targets of mutation in a variety of human cancers.

A new therapy for metastatic colorectal cancer that has been granted fast track designation by the U.S. Food and Drug Administration is being tested in a phase 3 clinical trial at Vanderbilt-Ingram Cancer Center.

A selenium transport protein produced in the colon is underexpressed in patients with ulcerative colitis and helps protect against colitis-associated cancer in an animal model, Vanderbilt investigators have discovered.

Andrea Birch was 9 years old and on top of the world.

Population-wide screening for genetic variants linked to hereditary breast and ovarian cancer may be cost effective in women between the ages of 20 and 35, according to a study published in JAMA Network Open.

Breast-conserving surgery (BCS) plus radiotherapy is the standard-of-care for women diagnosed with early-stage breast cancer.

Josh Peterson, MD, MPH, professor of Biomedical Informatics and Medicine, has been named director of the Center for Precision Medicine at Vanderbilt University Medical Center, effective since Oct. 1.