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This phase II trial studies the effect of hypofractionated radiotherapy followed by surgery in treating patients with soft tissue sarcoma. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects. Giving hypofractionated radiotherapy followed by surgery may allow patients with sarcomas to be treated in a much more rapid and convenient fashion.
This clinical trial studies the effect of the ERAS pain management method in managing pain after surgery in patients with extremity soft tissue sarcoma. Enhanced Recovery After Surgery, or ERAS, is a pain management method that places emphasis on managing risk factors (things like smoking, nutrition and fitness), using multiple types of pain control, and early movement, with the goal of improving patient outcomes. ERAS has been shown to reduce the length of time some patients stay in the hospital, reduce complications from surgery, and even lower costs of some surgeries. ERAS is designed may help cut down on the use of these narcotics in managing the pain of surgery patients. The purpose of this trial is to demonstrate that ERAS is safe and effective for patients having surgery to treat their sarcoma. Specifically, this study will look at using a non-narcotic pain management program that includes other methods of managing the pain of sarcoma surgery patients.

Frank Tong, Ph.D.

  • Centennial Professor of Psychology
  • Professor of Ophthalmology and Visual Sciences

Frank Tong, Ph.D.

  • Centennial Professor of Psychology
  • Professor of Ophthalmology and Visual Sciences

frank.tong@Vanderbilt.Edu

Research Program

Research Description

Have any questions? Contact Us 1-877-936-8422 for more information

Karen Winkfield, MD, PhD

  • Associate Director for Community Outreach and Engagement
  • Executive Director, Meharry-Vanderbilt Alliance
  • Ingram Professor of Cancer Research
  • Professor of Radiation Oncology

Karen Winkfield, MD, PhD

  • Associate Director for Community Outreach and Engagement
  • Executive Director, Meharry-Vanderbilt Alliance
  • Ingram Professor of Cancer Research
  • Professor of Radiation Oncology

karen.winkfield@Meharry-Vanderbilt.Org

Research Program

Have any questions? Contact Us 1-877-936-8422 for more information

Nikhil Khankari, Ph.D., M.P.H.

  • Assistant Professor of Medicine

Nikhil Khankari, Ph.D., M.P.H.

  • Assistant Professor of Medicine

nikhil.khankari@vumc.org

Research Program

Have any questions? Contact Us 1-877-936-8422 for more information

Josh Peterson, M.D., M.P.H.

  • Director, Center for Precision Medicine
  • Professor of Biomedical Informatics
  • Professor of Medicine

Josh Peterson, M.D., M.P.H.

  • Director, Center for Precision Medicine
  • Professor of Biomedical Informatics
  • Professor of Medicine

josh.peterson@vumc.org

Research Program

Have any questions? Contact Us 1-877-936-8422 for more information

Jason Schwartz, M.D., Ph.D.

  • Assistant Professor of Pediatrics

Jason Schwartz, M.D., Ph.D.

  • Assistant Professor of Pediatrics

jason.schwartz@vumc.org

Research Program

Have any questions? Contact Us 1-877-936-8422 for more information

Lisa Bastarache, M.S.

  • Research Associate Professor

Lisa Bastarache, M.S.

  • Research Associate Professor

lisa.bastarache@vumc.org

Research Program

Have any questions? Contact Us 1-877-936-8422 for more information
This trial studies the impact of indwelling tunneled pleural drainage systems (gravity or vacuum based) on pain in patients with plural effusion that has come back (recurrent). Vacuum drainage and gravity drainage are two commonly used drainage methods. Studying the best drainage methods may help future patients undergoing indwelling tunneled pleural catheter placement.
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